Desensitization of a balance with Langmuir binding of weights
نویسنده
چکیده
A balance is described with Langmuir binding of weights to each side. This simple physical system, when coupled with a previously derived equation for the equivalent displacement of weight that perturbs the equilibrium of a balance, models twostate, receptor systems in pharmacology for receptor activation. Surprisingly, this system also shows desensitization similar to many drug-receptor systems. Although understanding the biophysics behind receptor signaling is an important endeavor by itself, this analogy with a simple balance may bring new insights into other areas of physics as well.
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